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The Nature Podcast highlights of 2025

You have full access to this article via your institution. Download the Nature Podcast 24 December 2025 In this episode:

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peer reviews created using AI can avoid detection

The difficulty of detecting AI-tool use in peer review is proving problematic.Credit: BrianAJackson/iStock via Getty It’s almost impossible to know

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Dogma-defying signalling through G proteins could lead to better pain relief

Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-03810-1 Unexpected behaviours in G proteins could be exploited to design next-generation opioid drugs

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Tracing pollution in the lives of Arctic seabirds

High up in the Arctic Circle, Olivier Chastel begins his working day by scanning the horizon for polar bears, rifle

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China leads research in 90% of crucial technologies β€” a dramatic shift this century

China produces the largest share of high-quality research for 66 technologies.Credit: Liu Guoxing/VCG via Getty China is leading research in

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What will be the first AI-designed drug? These disease-fighting antibodies are top contenders

An illustration of antibodies (pink) binding to a flu virus (brown).Credit: Juan Gaertner/Science Photo Library Biologists achieved a landmark in

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AI is saving time and money in research β€” but at what cost?

More than 60% of researchers surveyed about AI say they use it for work.Credit: MD Abu Sufian Jewel/NurPhoto via Getty

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A bothy among the stars

It took the last traces of Homo sapiens 10,000 desperate years to reach the semi-oxygenated rock orbiting Proxima Centauri. Widely

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Laser cooling traps more antimatter atoms than ever before

Researchers have trapped more atoms of antimatter more quickly than ever before β€” a potentially transformative step in elucidating the

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Major AI conference flooded with peer reviews written fully by AI

An AI-detection tool developed by Pangram labs found that peer reviewers are increasingly using chatbots to draft responses to authors.Credit: